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Yi-Ru Chen Selected Research

nano-diamino-tetrac

1/2020NDAT Targets PI3K-Mediated PD-L1 Upregulation to Reduce Proliferation in Gefitinib-Resistant Colorectal Cancer.
12/2018Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation.
10/2018Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers.
10/2018Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells.

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Yi-Ru Chen Research Topics

Disease

20Neoplasms (Cancer)
01/2022 - 09/2017
9Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 01/2018
5Neoplasm Metastasis (Metastasis)
01/2022 - 01/2018
5Mouth Neoplasms (Oral Cancer)
07/2020 - 10/2018
4Colonic Neoplasms (Colon Cancer)
01/2022 - 01/2018
4Stomach Neoplasms (Stomach Cancer)
05/2021 - 11/2020
3Obesity
06/2022 - 11/2019
3Inflammation (Inflammations)
02/2021 - 11/2019
2Osteoarthritis
02/2021 - 02/2019
2Breast Neoplasms (Breast Cancer)
01/2021 - 04/2020
2Hepatocellular Carcinoma (Hepatoma)
09/2020 - 11/2019
2Alzheimer Disease (Alzheimer's Disease)
04/2020 - 01/2016
2Ovarian Neoplasms (Ovarian Cancer)
11/2019 - 01/2018
1Endometriosis
06/2022
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2021
1Neuroblastoma
11/2021
1Bacterial Infections (Bacterial Infection)
12/2020
1Liver Cirrhosis (Hepatic Cirrhosis)
11/2020
1Fibrosis (Cirrhosis)
11/2020
1Chronic Hepatitis B
05/2020
1Starvation
10/2019
1Cholangiocarcinoma
12/2018
1Leiomyoma (Uterine Fibroids)
10/2018
1Myoma
10/2018
1Prostatic Neoplasms (Prostate Cancer)
02/2018

Drug/Important Bio-Agent (IBA)

10ResveratrolIBA
04/2020 - 09/2017
9Thyroid HormonesIBA
07/2020 - 09/2017
9IntegrinsIBA
04/2020 - 01/2018
6Proteins (Proteins, Gene)FDA Link
09/2020 - 01/2018
6Thyroxine (Levothyroxine)FDA LinkGeneric
10/2019 - 01/2018
5tetraiodothyroacetic acid (TA(4))IBA
07/2020 - 01/2018
4Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2020
4nano-diamino-tetracIBA
01/2020 - 10/2018
3Biological ProductsIBA
01/2022 - 07/2020
3Peptides (Polypeptides)IBA
04/2020 - 01/2016
3B7-H1 AntigenIBA
10/2019 - 01/2018
3Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2018 - 01/2018
2Long Noncoding RNAIBA
01/2022 - 01/2021
2CytokinesIBA
02/2021 - 10/2019
2Pharmaceutical PreparationsIBA
07/2020 - 01/2019
2heteroneminIBA
07/2020 - 12/2018
2PolyphenolsIBA
04/2020 - 09/2017
2StilbenesIBA
04/2020 - 10/2018
2Hormones (Hormone)IBA
04/2020 - 01/2018
2Amyloid (Amyloid Fibrils)IBA
04/2020 - 01/2016
2Gefitinib (Iressa)FDA Link
01/2020 - 12/2018
2Cell Surface ReceptorsIBA
09/2019 - 09/2018
2Messenger RNA (mRNA)IBA
12/2018 - 10/2018
2CateninsIBA
01/2018 - 01/2018
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
06/2022
1Dehydroepiandrosterone (DHEA)IBA
06/2022
1Fatty Acids (Saturated Fatty Acids)IBA
01/2022
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2021
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2021
1Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
11/2021
1CoumarinsIBA
11/2021
1Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2021
1MicroRNAs (MicroRNA)IBA
05/2021
1PhytochemicalsIBA
02/2021
1SilymarinIBA
02/2021
1FlavonoidsIBA
02/2021
1NucleotidesIBA
01/2021
1Membrane Proteins (Integral Membrane Proteins)IBA
12/2020
1C-Reactive ProteinIBA
12/2020
1chrysophanic acidIBA
11/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2020
1LipopolysaccharidesIBA
11/2020
1hepatitis B virus X proteinIBA
11/2020
1Histones (Histone)IBA
09/2020
1Lysine (L-Lysine)FDA Link
09/2020
1ChromatinIBA
09/2020
1DNA (Deoxyribonucleic Acid)IBA
05/2020
1Progestins (Progestagens)IBA
04/2020
1Estrogens (Estrogen)FDA Link
04/2020
1SteroidsIBA
04/2020
1Dihydrotestosterone (Androstanolone)IBA
04/2020
1Androgen Receptors (Androgen Receptor)IBA
04/2020
1Nuclear Proteins (Protein, Nuclear)IBA
04/2020
1Steroid Receptors (Steroid Receptor)IBA
04/2020
1Flavin-Adenine Dinucleotide (FAD)IBA
04/2020
1Hematoxylin (Haematoxylon)IBA
01/2020
1Coloring Agents (Dyes)IBA
01/2020
1Eosine Yellowish-(YS) (Eosin)IBA
01/2020
1LeptinIBA
11/2019
1AmylasesFDA Link
10/2019
114-3-3 Proteins (14-3-3 Protein)IBA
10/2019
1Starch (Cornstarch)IBA
10/2019
1EnzymesIBA
10/2019
1SugarsIBA
10/2019
1Hyaluronic Acid (Hyaluronan)IBA
02/2019
1RNA (Ribonucleic Acid)IBA
12/2018
1Transcription Factors (Transcription Factor)IBA
12/2018
1Transforming Growth Factors (Transforming Growth Factor)IBA
12/2018
1Matrix Metalloproteinases (MMPs)IBA
12/2018
1Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA
12/2018
1Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
10/2018
1Insulin-Like PeptidesIBA
10/2018

Therapy/Procedure

6Therapeutics
01/2021 - 01/2018
2Chemoprevention
01/2021 - 01/2018
1Drug Therapy (Chemotherapy)
01/2020